WASHINGTON — President Donald Trump unveiled a $1.15 trillion budget on Thursday, a far-reaching overhaul of federal government spending that slashes many domestic programs to finance a significant increase in the military and make a down payment on a U.S.-Mexico border wall.

Trump’s proposal seeks to upend Washington with cuts to long-promised campaign targets like foreign aid and the Environmental Protection Agency as well as strong congressional favorites such as medical research, help for homeless veterans and community development grants.

“A budget that puts America first must make the safety of our people its number one priority — because without safety, there can be no prosperity,” Trump said in a message accompanying his proposed budget that was titled “America First: A Budget Blueprint to Make America Great Again.”

The $54 billion boost for the military is the largest since President Ronald Reagan’s Pentagon buildup in the 1980s, promising immediate money for troop readiness, the fight against Islamic State militants and procurement of new ships, fighter jets and other weapons. The 10 percent Pentagon boost is financed by $54 billion in cuts to foreign aid and domestic agencies that had been protected by former President Barack Obama.

The budget goes after the frequent targets of the party’s staunchest conservatives, eliminating the National Endowment for the Arts, legal aid for the poor, low-income heating assistance and the AmeriCorps national service program established by former President Bill Clinton.

Such programs were the focus of lengthy battles dating to the GOP takeover of Congress in 1995 and have survived prior attempts to eliminate them. Lawmakers will have the final say on Trump’s proposal in the arduous budget process, and many of the cuts will be deemed dead on arrival.